Side-effects of the injection
The injection will affect each person differently. Some people experience side effects and others don’t. It’s a good idea to keep a record of any side effects that you’re worried about.
These side effects do not affect your health. But they can affect your life, in good or bad ways.
It can cause irregular bleeding
The contraceptive injection changes the pattern of your bleeding. Your periods may stop or you might have irregular bleeding. This is when your bleeding does not happen at the same time each month.
Read more about irregular bleeding.
We sometimes recommend the contraceptive injection for people who have problems with their periods, because it can cause the bleeding to stop. For example, it can be a good choice if you have:
premenstrual syndrome
heavy periods
painful periods
endometriosis
Although some people have no bleeding from the start, irregular bleeding is very common in the first 6 months, and then gradually settles. This is not dangerous in any way:
after 3 months of taking the injectable contraceptive, 10% of people have no bleeding
after 12 months of taking the injectable contraceptive, 50% of people have no bleeding
1 in 100 people have ongoing problems with irregular bleeding on the injectable contraceptive – not everyone stops their period
Depending on how it affects you, the change in bleeding pattern may be an advantage or a disadvantage. If you have a lot of irregular bleeding, it can be very inconvenient. If you have very light irregular bleeding, it may not bother you.
It can cause weight gain
Some people experience weight gain when using the contraceptive injection. This might be because it can increase appetite, so you might feel hungrier and eat more than usual. Weight gain is more common if you are:
under the age of 18
have a BMI (body mass index) of over 30
If you gain more than 5% of your body weight in the first 6 months of using the contraceptive injection, it's likely you'll continue to gain weight.
Acne, headaches, hot flushes and vaginal irritation
Acne, headaches, hot flashes and vaginal irritation are some of the symptoms reported by people using contraceptive injections, but they’re also commonly reported by people who aren’t using them.
At the moment there’s no research evidence supporting a link between these symptoms and the injections. But, as with all kinds of contraception, if you get these symptoms and think they’re linked to your injectable contraceptive, you might want to try a different kind of contraception.
Explore different types of contraception.
Mood changes - a review of the evidence
There’s conflicting evidence about whether there’s a link between the contraceptive injection and low mood or depression. Some studies show there’s an increased risk, and others show there’s not an increased risk.
One study followed new contraceptive method users. There was no significant difference in nervousness or depression when comparing users of Depo Provera and users of non-hormonal methods of contraception.
On the other hand, another study found that Depo Provera users had a 44% greater risk of depressive symptoms than those not using it.
Another review of many different published studies didn’t find any evidence linking depression to taking progestogen methods of contraception such as the injection.
What to do if you experience side effects
Everyone experiences different types of hormonal contraception differently. If you're getting side effects that you do not like, keep a record of how you feel on it, then try a different method to see whether it’s any better.
Sometimes it can be hard to know if any symptoms you have are because of your contraception or something else.
We recommend that you:
keep a record of any side effects to see how they change over time
discuss it with your clinician, particularly if it carries on after using the contraception for 3 months
stop if you have unpleasant side effects over a longer period of time, and try an alternative method of contraception
Sometimes it takes a lot of trial and error before finding the right method of contraception for you. And what’s right for you may change over time. So just because one method suited you in the past, doesn’t mean it will suit you now.
Everything you wanted to know about sexual health and wellbeing - your questions answered by our expert team.